Multiplexed-engineered, iPSC-derived CAR T Cell Targets Proteins Expressed on Cancer Cells in Response to Cellular Stress and Malignant ...

Blocking a protein that imports lactic acid, a metabolic byproduct of cancer cells, reinvigorated exhausted T cells and led to improved tumor control in mouse models of cancer, according to a new ...

This valuable study reveals extensive binding of eukaryotic translation initiation factor 3 (eIF3) to the 3' untranslated regions (UTRs) of efficiently translated mRNAs in human pluripotent stem ...

Ulcerative colitis (UC) is a chronic gut inflammatory condition affecting the colon in humans. This study uses human samples as well as a mouse model of colitis induced by a chemical, DSS, to ...

CTX112 is a next-generation, wholly-owned, allogeneic CAR T product candidate targeting Cluster of Differentiation 19 ... in adult patients with relapsed or refractory CD19-positive B-cell ...

The researchers also assessed the correlation between the levels of **specific immune cell types—**Cluster of Differentiation ...

The development of CAR-T technology in recent years has been a major milestone in the fight against cancer. These sort of ...

Treatment with AUTX-703 resulted in notable cell differentiation and tumor growth inhibition in various primary cancer modelsAUTX-703 IND ...

differentiation, and effector functions. Lipid Metabolism in Immune Cells: Studies on how metabolic pathways of lipid synthesis, modification, and degradation influence the function of different ...

What keeps some immune systems youthful and effective in warding off age-related diseases? In new research done on mice, USC ...

B cells are a type of white blood cell. They make antibodies -- proteins that fight viruses and bacteria. B cells normally can’t cross from your blood into your brain or spinal cord. If you have ...