Fig. 3. Brightness and spectral stability of StarBright Dye conjugated CD4 antibodies after staining in common buffers. Red cell lysed human peripheral blood was stained with mouse anti-human CD4 ...

The main cells that HIV infects are those carrying a receptor molecule called CD4 on their surface. CD4 is found on immune cells, most particularly on T-helper cells and on macrophages. HIV gets ...

Before fusion of the HIV viral envelope and host cell membrane can occur, an HIV glycoprotein complex consisting of glycoproteins gp41 and gp120 must bind with the CD4 receptor on the membrane of ...

These include fusion inhibitors, CCR5 inhibitors and attachment inhibitors. In order to enter a host cell, HIV must bind to two separate receptors on the cell’s surface: the CD4 receptor and a ...

Panel A shows a circulating leukemic hairy cell (arrow) in a peripheral-blood smear (May–Grünwald–Giemsa stain ... chimeric antigen receptor T-cell products, or T-cell–redirecting ...

and selectively inhibits the interaction between the virus and cellular CD4 receptors 1 Previous studies identified amino acid positions in gp120 where substitutions or polymorphisms have the ...

Ulcerative colitis (UC) is a chronic gut inflammatory condition affecting the colon in humans. This study uses human samples as well as a mouse model of colitis induced by a chemical, DSS, to ...