Is the cost of research aimed at curing HIV worth it, when HIV can be effectively managed and prevented by existing drugs?

Herpes simplex virus (HSV-1), the microbial culprit behind oral herpes, infects up to 67 percent of adults under 50 worldwide, although most cases are asymptomatic. Like all viruses, HSV-1 requires a ...

A cold sore might seem like a minor nuisance. But behind that tingling lip is one of the world’s most widespread and cunning ...

Almost all cervical cancers are caused by human papillomaviruses (HPVs). In most cases, HPV DNA is integrated into the human genome. We found that tumor-specific, HPV-human DNA junctions are ...

The 2025 Warren Alpert Foundation Prize has been awarded to three scientists whose discoveries culminated in the development ...

That’s how the virus evades antiretroviral drugs and the body’s immune system. “HIV treatment is lifesaving but also lifelong,” said Dr. Patrick Jackson, one of the two lead authors on the paper ...

Sundquist’s research focuses on understanding how the HIV virus is built on a molecular level and how it interacts with the body to infect and spread through cells. By purifying and analyzing the ...

Once inside the host cell, the capsid is shed, and the virus begins copying itself. Lenacapavir stops that from happening. Structure of the HIV virus, showing the capsid protein shell and reverse ...

When the virus is moving to infect human T cells, the best link it has is the T cells' CD4 receptors on those. Once the virus binds to the CD4 receptor, the viral glycoprotein is triggered to open, ...

As the HIV virus glides up outside a human cell to dock and possibly inject its deadly cargo of genetic code, there's a spectacularly brief moment in which a tiny piece of its surface snaps open ...

UChicago chemists assemble massive model of the nuclear pore complex and HIV-1 virus capsid. ... which enters a host cell’s nucleus and forces the cell to make copies of the key HIV components. ...