Discover the potential of macrocycles in drug discovery: flexible, cell-permeable molecules targeting undruggable proteins.

Now, Scripps Research scientists have uncovered new structures of transthyretin. Their findings, published in Nature Structural & Molecular Biology on January 22, 2025, show how the three-dimension ...

Quantum computing and artificial intelligence (AI) can be combined with classical computing methods to design and discover small-molecule candidates that target the cancer-driving KRAS protein, ...

A serial entrepreneur and a promising drug emerge from failed companies to pursue subsets of obesity patients, with or ...

AI's hallucinations can drive drug discovery breakthroughs by generating novel molecular structures. Artificial intelligence ...

Cofounded by Dr. Siddhartha Mukherjee and Reid Hoffman, Manas AI leverages proprietary AI, generative computational chemistry ...

Wen Shuhao helped speed up the development of Pfizer’s Covid oral drug, Paxlovid. Now the chairman of Xtalpi wants to help ...

This shift in focus is expected to significantly enhance the utility of DECLs in drug discovery, allowing for the identification of lead compounds ... yield novel small molecule binders for ...

Researchers at Cedars-Sinai developed PR-364, a drug that prevented heart failure in mice after heart attacks. The treatment ...

Appoints Simon Harnest as Chief Financial Officer to advance capital markets and corporate development strategy supporting TOS-358, the Company's lead covalent PI3Kα inhibitor, and additional programs ...

BenevolentAI has entered a two-year agreement with the MRC Technology to investigate new small molecule and antibody drug candidates ... s screening and hit to lead capabilities, is powerful ...

Hoffman isn’t the only prominent Silicon Valley figure betting on A.I.’s promise in medical research. The new technology is ...