Powerball numbers and jackpot results for $264 million lottery drawing Wednesday. Who won? Winning numbers, next drawing, tickets and more.

The winning numbers from the Wednesday, July 16 drawing are 4, 21, 43, 48 and 49. The Powerball was 22 . The Power Play multiplier was 2x. Check back to see if anyone won the Powerball jackpot.

The Powerball lottery jackpot was an estimated $264 million with a cash option of $119.7 million for Wednesday night's drawing.

A 65-year-old woman from Tuscola County won more than $865,000 from the Michigan Lottery's fast cash jackpot at the ...