Seth Shipman is a magpie of biological innovation. He collects useful parts — from bacteria, nerve cells, reams of genetic data — and transforms them into tools that do amazing things.

"We wanted to push the boundaries of genomic technologies by engineering tools to help us study the true complexity of biology and disease," says Associate Investigator Seth Shipman, Ph.D., senior ...

Shipman and his colleagues began by creating retrons that produce DNA sequences specifically designed to edit invading phages—a system the team dubbed "recombitrons." Then, they put those ...

Seth Shipman (right), Alejandro González-Delgado (left), and their colleagues at Gladstone Institutes closely examined never-before-tested retrons, bacterial defense systems that can be leveraged ...

A team of Harvard scientists led by geneticists Seth Shipman and Jeff Nivala has just developed a fascinating way to write chunks information into the genetic code of living, growing bacterial ...

Now, a team led by Dr. Seth Shipman at Gladstone Institutes engineered a biological recorder—dubbed Retro-Cascorder—that, like an old school camcorder, can capture a cell’s gene expression history on ...

The National Institutes of Health (NIH) has granted an NIH Director's New Innovator Award to Seth Shipman, PhD, assistant investigator at Gladstone Institutes. The award will support the ...

Seth Shipman, Ph.D., a postdoctoral researcher in the lab of famed geneticist George Church, led the team in the process. Left: The original image that scientists pixelated to make it easier to ...

The team was able to achieve 90% accuracy: "We were really happy with how it came out," Seth Shipman told me. Eventually, the team wants to use the technique to create "molecular recorders".

Beyond just storing data, Seth Shipman, a scientist working in Church’s lab at Harvard who led the study, says he wants to use the technique to make “living sensors” that can record what is ...

Alejandro González-Delgado, Santiago C. Lopez, Matías Rojas-Montero, Chloe B. Fishman, Seth L. Shipman. Simultaneous multi-site editing of individual genomes using retron arrays.