Discover the potential of macrocycles in drug discovery: flexible, cell-permeable molecules targeting undruggable proteins.

EPFL researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel ...

Health systems will work to expand their supply chains and ink nontraditional partnerships in 2025, while trimming excessive ...

Received supportive FDA feedback on key elements of the potential ELI-002 Phase 3 study design, including dose, schedule, patient population and ...

An interview on how advanced techniques can be used to enhance silk fibroin and chitosan for drug delivery applications.

Scientists have used deep learning to design new proteins that bind to complexes involving other small molecules like hormones or drugs, opening up a world of possibilities in the computational design ...

Scientists have taken a major step forwards in tackling one of the greatest abiding challenges in chemistry, by learning how to program the self-assembly of molecules in such a way that the end result ...

With the use of deep learning and advanced algorithms, generative AI can promote acceleration in the design and development ...

Predicting drug–target binding affinity (DTA ... our goal is to design efficient and accurate prediction methods that effectively handle the sequence information. Based on our observation, there are ...

The new drug has yet to be approved ... That cuts across both target identification and molecule design, and can potentially introduce biases. US-based Recursion Pharmaceuticals says its approach ...

The Family are now the Garda National Drugs and Organised Crime Bureau’s number one target. The gang were elevated to the position due to their willingness to use violence in recent years and ...

They've been able to keep their hard line in the sand when it comes to the amount of money they're willing to pay, while also still having a chance to sign their dream target based on the lack of ...