A tailored cocktail of genes can reprogram a subset of progenitors to no longer produce glial cells and instead develop into neurons involved in motor control.

A primary constraint for mitochondrial repression is access to cytosolic inorganic phosphate, which is determined by the glycolytic flux rate.

Open annotations (there are currently 0 annotations on this page). Back in January 2023, we switched to a new way of publishing research. Since then we’ve reached more than 10,000 submissions, so ...

This study presents valuable findings from an observational dataset in a riverine ecosystem about the effects of genetic and species diversity, across multiple trophic levels, on ecosystem functions.

Here, we show that the timing of blastomere polarization at the 8-cell stage is asynchronous, and that the heterogeneity between the blastomeres at the 4-cell stage influences cell fate specification ...

Repurposing of a drug designed for pain relief can quickly and reversibly slow biochemical and metabolic activities in cells and organs and could facilitate organ transplantation and prevent tissue ...

The raw mass spectrometry data was deposited in the PRIDE repository:Project Name: Spatially restricted proteomics reveals dynamic changes in the caveolin-1 interactome in response to increased membra ...

We show that pharmacological elevations of noradrenergic but not glucocorticoid activity after retrieval impair subsequent remembering. These impairments were bound to strong hippocampal and cortical ...

However, there is a lack of knowledge about how externally applied currents affect neuronal spiking activity in cerebellar circuits in vivo. We investigated how Cb-tDCS affects the firing rate of ...

Dementia Research Institute, School of Medicine, Cardiff University, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ, UK Neuroscience and Mental Health Innovation Institute, School of Medicine, ...

Computational principles shed light on why movement is preceded by preparatory activity within the neural networks that control muscles.

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. In this study, the ...