A tailored cocktail of genes can reprogram a subset of progenitors to no longer produce glial cells and instead develop into neurons involved in motor control.

Open annotations (there are currently 0 annotations on this page). Back in January 2023, we switched to a new way of publishing research. Since then we’ve reached more than 10,000 submissions, so ...

This study presents valuable findings from an observational dataset in a riverine ecosystem about the effects of genetic and species diversity, across multiple trophic levels, on ecosystem functions.

Here, we show that the timing of blastomere polarization at the 8-cell stage is asynchronous, and that the heterogeneity between the blastomeres at the 4-cell stage influences cell fate specification ...

The raw mass spectrometry data was deposited in the PRIDE repository:Project Name: Spatially restricted proteomics reveals dynamic changes in the caveolin-1 interactome in response to increased membra ...

However, there is a lack of knowledge about how externally applied currents affect neuronal spiking activity in cerebellar circuits in vivo. We investigated how Cb-tDCS affects the firing rate of ...

Computational principles shed light on why movement is preceded by preparatory activity within the neural networks that control muscles.

Chromatin immunoprecipitation (ChIP-seq) is the most common approach to observe global binding of proteins to DNA in vivo. The occupancy of transcription factors (TFs) from ChIP-seq agrees well with ...

Ache Lab, Neurobiology and Genetics, Theodor-Boveri-Institute, Biocenter, Julius-Maximilians-University of Würzburg, Am Hubland, 97074 Würzburg, Germany Zandawala Lab, Neurobiology and Genetics, ...

Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, NYC, NY, USA Department of Medicine, New York University Grossman School of Medicine, NYC, NY, ...

Ubiquitination typically involves covalent linking of ubiquitin (Ub) to a lysine residue on a protein substrate. Recently, new facets of this process have emerged, including Ub modification of ...