The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...

Rheumatoid arthritis (RA) is associated with heart and lung dysfunction. Current therapies fail to attenuate such complications. Here, we identify formyl-peptide receptor type 2 (FPR2) as a ...

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N6-methyladenosine (m 6 A) exerts many of its regulatory effects on eukaryotic mRNAs by recruiting cytoplasmic YT521-B homology-domain family (YTHDF) proteins. Here, we show that in Arabidopsis ...

EMBO Press publishes five scientific journals: The EMBO Journal - Submit here The EMBO Journal has been EMBO's flagship publication for 40 years. With a scope that spans all areas of molecular biology ...

Neural stem cells (NSCs) in the mammalian brain decline rapidly with age, leading to impairment of hippocampal memory function in later life. However, the relationship between epigenetic remodeling ...

Arabidopsis genome encodes approximately 60 putative MAPKKKs, 10 MAPKKs, and 20 MAPKs (MAPK‐Group, 2002).MAPK cascades have been shown to regulate diverse aspects of plant biology, including plant ...

Chloride (Cl −) ions cause major damage to crops in saline soils.Understanding the key factors that influence Cl − uptake and translocation will aid the breeding of more salt-tolerant crops. Here, ...

Macrophages not only clean the wound early for repair, but are also critically involved in all subsequent phases of proliferation and regeneration (Mirza et al, 2009; Shook et al, 2016).They ...

This cover highlights the article Early coordination of cell migration and cardiac fate determination during mammalian gastrulation by Shayma Abukar, Kenzo Ivanovitch and colleagues. Using long-term ...

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TP53-mutant acute myeloid leukemia (AML) and myelodysplastic neoplasms (MDS) are characterized by chemotherapy resistance and represent an unmet clinical need.Chimeric antigen receptor (CAR) T-cells ...