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  1. Scleroderma - Symptoms and causes - Mayo Clinic

    Jun 15, 2024 · Scleroderma (sklair-oh-DUR-muh), also known as systemic sclerosis, is a group of rare diseases that involve the hardening and tightening of the skin. Scleroderma also may …

  2. Scleroderma: Symptoms, Causes & Treatment Options

    Scleroderma is more likely to cause serious complications if it affects your ability to breathe or process nutrition. It can be fatal. Systemic sclerosis has three subtypes — diffuse, limited and …

  3. Scleroderma Symptoms, Types, Causes, & Risk Factors | NIAMS

    Scleroderma causes areas of tight, hard skin, but can also harm your blood vessels and organs. Learn the causes and treatments of this skin disease.

  4. Scleroderma - Johns Hopkins Medicine

    Scleroderma is an ongoing (chronic) disease that causes abnormal growth of connective tissue. It can affect the joints, skin, and internal organs. It is degenerative and gets worse over time.

  5. Scleroderma - Wikipedia

    Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs. [2][6][8] The disease can be either localized to the skin …

  6. Systemic Sclerosis (Scleroderma): Pictures, Symptoms, Causes

    Sep 11, 2025 · Systemic sclerosis (scleroderma) causes the body to destroy healthy tissue. It can change the appearance and texture of your skin and affect other organs.

  7. Scleroderma Symptoms - MedlinePlus

    Jun 6, 2024 · Scleroderma is an autoimmune disease that causes inflammation and thickening in the skin and other areas of the body. The exact cause of scleroderma is unknown.

  8. National Scleroderma Foundation

    Dec 22, 2025 · Our Mission The National Scleroderma Foundation’s mission is to advance medical research, promote disease awareness, and provide support and education to people …

  9. Scleroderma: Causes, Symptoms, and Treatment - WebMD

    Feb 27, 2024 · Scleroderma is a long-lasting autoimmune disease that affects your skin, connective tissue, & internal organs. Learn about types, causes, risk factors, symptoms, …

  10. About Scleroderma : Johns Hopkins Scleroderma Center

    Scleroderma – Patient Perspective The following Scleroderma Educational Program was developed by behavioral psychologist Dr. Jennifer Haythornthwaite and Johns Hopkins …